Muscle Relax Affects Outcomes of Robotic Surgery

• Status: Unknown status
• Trial end date: 2019-11-10
• Target enrollment: 0
• Participant gender: All

Summary

During robotic laparoscopic surgery, a high intraperitoneal pressure may result in high airway pressure and inadequate perfusion of the abdominal organs, and as a result the postoperative outcomes. Degree of neuromuscular blockade (NMB) can affect the intraperitoneal pressure. In this study, the patients undergoing robotic laparoscopic surgery will be assigned to deep NMB group and moderate NMB group. Perioperative outcomes including maximal intraperitoneal pressure, maximal intraoptic pressure, quality of emergence, postoperative pain, and incidence of postoperative respiratory complication will be compared. The results of this study will provide evidence for optimizing NMB protocol of robotic laparoscopic surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Air Force Military Medical University, China; Fourth Military Medical University
• Treatments: Bromides; Neuromuscular Blocking Agents; Rocuronium

Criteria

Inclusion Criteria:

• patients scheduled for elective robotic laparoscopic surgery under general anesthesia

• American Society of Anesthesiologists status 1-2

• Body mass index of 18-30kg/m2

• Patients scheduled to be positioned in trendelenburg position during surgery

Exclusion Criteria:

• Patients allergic to rocuronium

• Patients with neuromuscular dysfunction

• Patients with existed pulmonary diseases

• Patients with hepatic or renal dysfunction