Muscle Relaxants and Laryngeal Local Anesthetics for Laryngeal Mask Airway Insertion Decreasing Propofol in Elderly
Status:
Recruiting
Trial end date:
2024-03-04
Target enrollment:
Participant gender:
Summary
Laryngeal mask airway (LMA) is currently the most widely used supraglottic airway device with
advantages of simple and fast placement, reduced anesthesia drug use, more stable
hemodynamics, and less throat discomfort after anesthesia compared to endotracheal
intubation. Some studies claimed the use of muscle relaxants or local anesthetics (sprays or
lubricants containing local anesthetics) for the throat before LMA placement can reduce the
dosage of induction agents and postoperative throat complications.
In modern society, more and more elderly people undergo elective surgery with the need of
general anesthesia. However, they are the more vulnerable population with tendency of greater
hemodynamic changes with more induction agent usage. Propofol is one of the most used
induction agents which may lead to a drop in blood pressure. The objective of this study is
to observe whether the dose of propofol and the changes in hemodynamics can be reduced by
using muscle relaxants or laryngeal local anesthetics in elderly who receiving general
anesthesia with LMA insertion.