Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis.

• Status: Completed
• Trial end date: 2011-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether mycophenolate mofetil is superior to azathioprine to prevent flares of lupus nephritis.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Frédéric A. Houssiau, MD, PhD
• Treatments: Azathioprine; Mycophenolate mofetil; Mycophenolic Acid

Criteria

Inclusion Criteria:

• SLE aged ≥ 14 years

• Proteinuria ≥ 500 mg/day

• Biopsy-proven proliferative lupus nephritis

Exclusion Criteria:

• Recent treatment with high-dose glucocorticoids

• Recent treatment with immunosuppressive drugs

• More exclusion criteria in the protocol