Myo-Inositol- Based Co-treatment in Women With PCOS Undergoing Assisted Reproductive Technology

• Status: Recruiting
• Trial end date: 2021-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

This is a prospective comparative randomized controlled study investigating the effect of Myo-Inositol-based co-treatment on oocyte quality measures in women with PCOS.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: American University of Beirut Medical Center
• Treatments: Folic Acid; Inositol

Criteria

Inclusion Criteria:

• Age 18-40 years at the time of enrollment.

• Women diagnosed with PCOS according to the Rotterdam criteria indicated by oligoamenorrhea (six or fewer menstrual cycles during a period of 1 year), hyperandrogenism (hirsutism, acne, or alopecia) or hyperandrogenemia (elevated levels of total or free T) and typical features of ovaries on ultrasound scan.

• Planned IVF/ICSI treatment.

• Normal uterine cavity (as assessed by hysteroscopy or HSG).

• Normal hormonal investigation: TSH and PRL.

Exclusion Criteria:

• Azoospermia.

• Other medical conditions causing ovulatory disorders, such as hyperprolactinemia, hypothyroidism, or adrenal hyperplasia.

• Hypersensitivity to Myo-Inositol or its derivatives.