Myocardial Function & FFA Metabolism in HIV Metabolic Syndrome
Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
We hypothesize that the hearts of HIV+ people with The Metabolic Syndrome use and oxidize
fats and sugars inappropriately, and that this may impair the heart's ability to pump blood.
We hypothesize that exercise training or pioglitazone (Actos) will improve fat and sugar
metabolism in the hearts of HIV+ people with The Metabolic Syndrome. This study will advance
our understanding of cardiovascular disease in HIV+ people, and will test the efficacy of
exercise training and pioglitazone for improving insulin resistance, heart metabolism and
heart function in this at risk population.
Phase:
N/A
Details
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)