Overview

Myocardial Infarction Triage and Intervention Project (MITI)

Status:
Completed
Trial end date:
1992-03-01
Target enrollment:
0
Participant gender:
All
Summary
To determine the practicality, benefit, and safety of paramedic administration of thrombolytic therapy for acute myocardial infarction. The feasibility of paramedics correctly identifying candidates for thrombolytic therapy following myocardial infarction was assessed in Phase I. In Phase II, pre-hospital thrombolytic therapy was compared with in-hospital thrombolytic therapy.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Washington
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Plasminogen
Tissue Plasminogen Activator
Criteria
Men and women, ages 35 to 71, with chest pain of between 15 minutes and 6 hours duration,
systolic blood pressure of more than 80 mm Hg and less than 200 mm Hg, and a diastolic
blood pressure of less than 120 mm Hg. (Phase I).

Men and women with m