Myocardial Perfusion in Type 2 Diabetes

• Status: Completed
• Trial end date: 2009-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators aimed to evaluate microvascular circulation with novel method: real-time myocardial contrast echocardiography in patients with type 2 diabetes and normal coronary arteries.

Myocardial blood flow reserve will be determined by quantitative contrast Stress echocardiography. Diabetic individuals will be evaluate in a decompensated state (Phase 1) and after optimization of medical treatment four months later (Phase 2).

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Sao Paulo General Hospital
• Collaborator: Fundação de Amparo à Pesquisa do Estado de São Paulo
• Treatments: Metformin

Criteria

Inclusion Criteria:

• Type 2 diabetes mellitus

• Normal echocardiogram

• Absence of obstructive epicardial coronary disease

Exclusion Criteria:

• Obstructive coronary disease

• Heart valve disease

• COPD

• Cardiac Arrhythmias

• Cardiomyopathy