Myocardial Protection With Adenosine Preconditioning

• Status: Completed
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Adenosine has been proved to be an important mediator of myocardial protection induced by ischemic preconditioning. The hypothesis of this study is that adenosine preconditioning can provide additional myocardial protection in the setting of pediatric open heart surgery with cardioplegia and cardiopulmonary bypass.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Xijing Hospital
• Treatments: Adenosine

Criteria

Inclusion Criteria:

• Clinical diagnosis of congenital heart defects eligible for surgery treatment under cardiopulmonary bypass and cardioplegia

• Body weight less than or equals to 10kg

Exclusion Criteria:

• Cardiac surgery is performed without cardiopulmonary or cardioplegia

• Body weight more than 10Kg