N-Acetyl Cysteine After Cervical Cerclage

• Status: Completed
• Trial end date: 2008-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of the study is to evaluate the effect of N-acetyl cysteine (NAC) on pregnancy outcome in women undergoing cervical cerclage for cervical insufficiency.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• women with history suggestive of cervical insufficiency together with ultrasound findings suggestive of cervical insufficiency undergoing elective cervical cerclage between the 11th and 12th gestational week.

• singelton viable fetus

Exclusion Criteria:

• women tested positive for bacterial vaginosis

• women currently with threatened abortion (vaginal bleeding or uterinecramps)

• age older than 35 years or younger than 20 years

• unwillingness to participate

• irregular and/or uncertain menstrual dates

• rupture of membranes

• previous cesarean delivery

• possible risks for preterm birth in the current or previous pregnancy such as twin pregnancy, IUFD, malpresentation, known fetal anomaly, progesterone or heparin treatment during the current pregnancy, hypertension, and/or seizure disorders.

• women with contra indications for cervical cerclage or anesthesia.