N-Acetylcysteine vs Placebo as Adjunctive Treatment in Pediatric Leukemia
Status:
Terminated
Trial end date:
2020-12-03
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to analyze the effect of N-Acetylcysteine administration
towards blood oxidant level, transaminase enzyme, and bilirubin level in ALL children who
undergo induction phase of chemotherapy. The main question it aims to answer is whether
N-Acetylcysteine can decrease oxidative stress level and reduce hepatotoxicity complication.
Participants will be evaluated for MDA level, transaminase enzymes and bilirubin level
before, during, and after the chemotherapy. Participants will be given capsules containing
600mg of N-Acetylcysteine as adjunctive treatment during the 6 weeks induction phase of
chemotherapy.
Researchers will compare the lab results to the placebo group to see if there is any
significant difference in the results.