The purpose of this study is to investigate the efficacy of N-acetylcysteine (NAC) for
smoking cessation in a double blind, randomized, placebo-controlled trial. Simultaneously,
the study aims to elucidate the role of inflammatory markers and oxidative stress related to
nicotine addiction and the use of NAC, an acetylated precursor of cysteine, a naturally
occurring amino acid that has antioxidant actions in its own right, in reducing oxidative
stress and inflammation in smokers. It will evaluate the use of NAC in smoking cessation,
after 4, 8 and 12 weeks of treatment.