N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as irinotecan and temozolomide, work in different
ways to stop tumor cells from dividing so they stop growing or die. Temozolomide may help
irinotecan kill more tumor cells by making them more sensitive to the drug. Cefixime may be
effective in preventing diarrhea that is caused by treatment with irinotecan.
PURPOSE: This phase I trial is studying the side effects and best dose of irinotecan when
given together with temozolomide and cefixime in treating young patients with recurrent or
resistant neuroblastoma.