N99-01: Combination Chemotherapy, Radiation Therapy, and Stem Cell Transplantation in Treating Patients With Neuroblastoma
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from
dividing so they stop growing or die. Giving the drugs in different ways may kill more tumor
cells. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell
or bone marrow transplantation may be able to replace immune cells that were destroyed by
chemotherapy or radiation therapy.
PURPOSE: This phase I trial is studying the side effects and best dose of combination
chemotherapy when given before stem cell transplant and radiation therapy in treating
patients with neuroblastoma that has not responded to previous treatments.
Phase:
Phase 1
Details
Lead Sponsor:
New Approaches to Neuroblastoma Therapy Consortium