NAC Effect on Iron Overload and Blood Transfusion in β-thalassemia Major

• Status: Not yet recruiting
• Trial end date: 2024-04-30
• Target enrollment: 0
• Participant gender: All

Summary

The effect of N_acetylcystein as an antioxidant on iron overload and frequency of blood transfusion in β-thalassemia major patients at Assiut Childern Hospital University And its cosubmitted for partial fulfillment of master degree in Pediatrics

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• thalassemia major children .

• On oral iron chelation .

Exclusion Criteria:

• change in the dose of iron chelation within 3 months before enrollement or during study period .

• Liver impairment

• Renal impairment

• patients not adeherent to therapy