Overview

NASPI: N-Acetylcysteine vs. Ascorbic Acid for Prevention of Contrast Induced Nephropathy in Renal Insufficiency Undergoing Coronary Catheterization

Status:
Completed

Trial end date:
2006-04-01

Target enrollment:

Participant gender:

Summary

The contrast induced nephropathy (CIN) has been known to be associated with significant clinical and economic consequences. Many studies were performed to find the pathophysiology and preventive measures for CIN. But the results were somewhat frustrating. Recently, it has been reported that the N-acetylcysteine and ascorbic acid might have preventive effects for CIN by their antioxidant effects.There have been no study to compare these two antioxidant.

Phase:

Phase 4

Details

Lead Sponsor:

Seoul National University Hospital

Treatments:

Acetylcysteine
Ascorbic Acid
N-monoacetylcystine