This study is a double blind, placebo controlled, ascending single and multiple oral dose
study conducted in two parts, aimed at determining the safety and tolerability of single and
multiple oral doses of NEO6860 in healthy subjects.
Key secondary objectives are: assessment of the pharmacokinetic profile, effect of food and
gender.
The analgesic effect of NEO6860 will be investigated using experimental capsaicin-evoked pain
methods.
Part A will comprise an ascending single dose, with 6 dose levels. Part B will comprise an
ascending multiple dose, with 2 dose levels.