Overview

NEoadjuvant Dose-dense MVAC In cOmbination With Durvalumab and Tremelimumab in Muscle-invasive Urothelial Carcinoma

Status:
Recruiting
Trial end date:
2025-09-01
Target enrollment:
Participant gender:
Summary
This is an open label, phase I/II clinical trial to evaluate the efficacy and safety of 2 cycles of durvalumab without (Arm A) or with (Arm B) tremelimumab in association with ddMVAC as neoadjuvant therapy in patients with MIUC.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie
Treatments:
Antibodies, Monoclonal
Durvalumab
Tremelimumab