NOrepinephrine and VasoprEssin Versus Norepinephrine aLone in Critically Ill Patients With Septic Shock
Status:
Withdrawn
Trial end date:
2017-11-27
Target enrollment:
Participant gender:
Summary
Sepsis, a systemic host response to the invasion of a pathogenic microorganism, may progress
to severe sepsis, wherein the patient experiences acute dysfunction in at least one organ
system, and further develop into septic shock if the patient cannot regain adequate systemic
blood pressure and perfusion after adequate and appropriate fluid resuscitation. Further
prospective study of the potential mortality benefit with combination norepinephrine and
vasopressin in critically ill patients with septic shock needs to be performed. Our research
will resolve this essential question and improve the scientific knowledge surrounding
vasoactive medications in patients with septic shock.