NSAID vs Steroid in Trabeculectomy Wound Management

• Status: Not yet recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will examine the efficacy of steroid vs NSAID treatment in relation to trabeculectomy wound management. Eligible study participants will be randomized to receive either steroid or NSAID topical treatment one week post-trabeculectomy. Each group will dose with their assigned study treatment until three months post-trabeculectomy. Study participants will be followed for twelve months post-trabeculectomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cindy Hutnik
• Collaborator: Glaucoma Research Society of Canada
• Treatments: BB 1101; Bromfenac; Dexamethasone; Dexamethasone acetate; Nepafenac

Criteria

Inclusion Criteria:

• Adult patients over the age of 18 years

• Uncontrolled open angle glaucoma

• Scheduled to undergo stand-alone trabeculectomy

• No previous incisional glaucoma surgery

• No ocular surgery of any kind in prior 6 months

Exclusion Criteria:

• steroids and/or NSAIDs contraindicated

• poor corneal epithelial health