NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain

• Status: Completed
• Trial end date: 2008-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators investigated whether a strictly controlled pain management with patients participating in a clinical study can attenuate persistence of post-thoracotomy pain. The investigators also wanted to find out whether NSAID + intravenous patient-controlled analgesia with morphine is an efficacious alternative to thoracic epidural analgesia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Helsinki University Central Hospital
• Collaborator: Academy of Finland
• Treatments: Bupivacaine; Diclofenac; Morphine; Parecoxib; Valdecoxib

Criteria

Inclusion Criteria:

• Patients scheduled for elective thoracotomy for lung surgery

Exclusion Criteria:

• Contraindication to any of the study drugs or an epidural catheter,

• Significant liver, renal or cardiac disease

• Peptic ulcer

• Regular use of analgesics

• Re-thoracotomy, and the patient´s inability to understand the use of PCA/patient controlled thoracic epidural analgesia (PCEA).