Nailfold Capillary Blood Flow With Latanoprost Bunod

• Status: Completed
• Trial end date: 2020-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to look at the relationship of small blood vessels irregularities observed with an imaging system called video nailfold capillaroscopy in people with primary open-angle glaucoma. Nailfold capillaroscopy (NFC) is a video camera with a magnifying lens used for studying the movement of blood in small blood vessels. It is simple, safe and does not penetrate the skin. The skin fold that is at the tip of the finger is called the "nailfold". NFC has been used to assess blood vessel narrowing in patients with glaucoma.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Icahn School of Medicine at Mount Sinai
• Treatments: Latanoprost

Criteria

Inclusion Criteria:

• 40 years old to 80 years old

• All participants will have open angles and no signs of secondary glaucoma such as exfoliation syndrome

• Untreated intraocular pressure (IOP) may be ≤ 21mmHg or ≥ 21mmHg in both eyes

• The cup-to-disc ratio (CDR) ≥ 0.6 in both eyes and CDR asymmetry ≤ 0.2.

• POAG patients will have reliable Humphrey Visual Field (HVF) loss consistent with optic nerve damage

• POAG patients can have any stage of POAG and be on any form of treatment for their disease.

• Willingness to sign informed consent and comply with study procedures.

Exclusion Criteria:

• History of non-POAG forms of glaucoma

• Pregnancy

• Inability to give informed consent