Naproxen for the Prevention of HO After Complex Elbow Trauma
Status:
Withdrawn
Trial end date:
2010-10-01
Target enrollment:
Participant gender:
Summary
Complex elbow fractures can lead to formation of new bone (called Heterotopic ossification).
This new bone is unwanted and it can restrict motion. This research study is being done to
learn more about the effect of the drug naproxen, on unwanted formation of new bone around
the elbow as it heals after a fracture. Naproxen belongs to a class of drugs called NSAIDs
which stands for non-steroidal anti-inflammatory drugs.
Several research studies suggest that NSAIDs such as Naproxen can prevent the unwanted
formation of new bone around the hip. The effect of NSAIDS on the formation of bone around
the elbow has not been studied as well as it has been studied for their effect on the hip.
The drug, Naproxen is approved by the US food and drug administration (FDA) for sale but ot
specifically for the treatment of heterotopic ossification.