Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures

• Status: Recruiting
• Trial end date: 2022-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate two drug options for pain control in patients following wrist injury. Participants will be randomized to one of the 2 pain relief treatments to determine what treatment provides the most effective pain relief

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lawson Health Research Institute
• Collaborator: Canadian Institutes of Health Research (CIHR)
• Treatments: Acetaminophen; Hydrocodone; Ibuprofen; Oxycodone

Criteria

Inclusion Criteria:

• All patients 18 and older undergoing non-operative management of a hand or wrist fracture will be considered eligible.

• Able to read and speak English

Exclusion Criteria:

• pain exceeding 7/10 on numeric rating scale or 35/50 on PRWE pain scale at enrollment

• nerve injury

• surgeon decision that surgery is required

• history of chronic opioid use

• documented or suspected substance abuse

• individuals currently on daily use of ibuprofen, acetaminophen or other pain-altering medication including medications like Neurontin (gabapentin) and Ultram (tramadol)

• individuals with documented or suspected chronic pain syndrome, reported allergy or adverse reaction to hydrocodone, acetaminophen, or ibuprofen

• history or symptoms of serious medical problem in the last year (i.e., arrhythmia, impaired cardiovascular function, gastrointestinal bleeding, liver disease, renal disease)

• patients with active peptic ulcer disease (history of severe heartburn)

• symptoms of infection

• pregnant or lactating women

• diagnosis of cognitive impairment

• unable to provide informed consent

• unable or unwilling to fill out the forms

• prior fracture in same hand

• on Coumadin or Plavix

• other medical or psychological health conditions that preclude them from receiving either intervention

• or unable to return for follow-up visits