Narrow-band Imaging, Autofluorescence Imaging and Gastroesophageal Reflux Disease

• Status: Unknown status
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Aim of this study is to compare the efficacy of narrow band imaging (NBI) and autofluorescence imaging (AFI) to distinguish subtle mucosal change related to acid reflux that is not visible in standard white light imaging (WLI) endoscopy, and help indicating the diagnosis of gastroesophageal reflux disease (GERD).

• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Chinese PLA General Hospital
• Treatments: Rabeprazole

Criteria

1. Inclusion criteria

• GERD symptom: heartburn or regurgitation (either one) at least 2 days a week

• Presence of symptom for longer than 1 month before screening

• Provision of written informed consent

2. Exclusion criteria:

• Any known esophageal disease or disorder, other than reflux esophagitis

• Active or healing gastroduodenal ulcer (except scars)

• History of esophageal or gastric surgery.

• Clinically significant heart, lung, liver or kidney disease

• Allergy to proton-pump inhibitor

• Pregnancy