Flexible nasendoscopy involves passing a soft, thin, endoscope through the nose. This
diagnostic procedure is often essential for assessment of a child by an Otolaryngologist in
outpatients. The purpose of this randomized controlled double-blind study is to determine
whether there is a difference in the degree of discomfort experienced by children undergoing
flexible nasendoscopy, after receiving one of three different intranasal sprays: (A) placebo
(isotonic saline solution), (B) decongestant (0.05% xylometazoline hydrochloride), or (C)
decongestant with local anesthetic (0.05% xylometazoline hydrochloride with 1% lidocaine
hydrochloride).
Null hypothesis: There is no difference in the degree of reported discomfort experienced
(using a validated pediatric pain score) by children undergoing flexible nasendoscopy, after
receiving either intra-nasal topical placebo, decongestant, or decongestant with local
anesthetic.
Phase:
Phase 4
Details
Lead Sponsor:
Children's & Women's Health Centre of British Columbia
Treatments:
Anesthetics Anesthetics, Local Ephedrine Lidocaine Nasal Decongestants Pseudoephedrine Xylometazoline