Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and
Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
Nasal resistance presents considerable variations during night[8]. Additionally, Oral and
oro-nasal breathing epochs exhibit strong correlation with the number of apnoea/hypopnoeas
[7].The hypothesis that the present study aims to test is whether the pharmacological
prevention of increased nasal resistance during night could alter breathing route pattern and
lead to a decrease in the number of apnoea/hypopnoeas in OSA patients with normal nasal
resistance.