Natural Cycle Versus Stimulated Cycle Before Frozen Embryo Transfer

• Status: Completed
• Trial end date: 2018-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

Embryo freezing is a technique used regularly to optimize the pregnancy rate in case of infertility. This method is performed in presence of supernumerary embryo(s) after fresh transfer, or after freeze all embryos in case of medical reasons. It is necessary to control that the transfer is performed when the endometrium is receptive, which is essential for embryo implantation and pregnancy. This period is defined as the "implantation window". Endometrial preparation can be achieved by hormone replacement therapy (HRT) or moderate ovarian stimulation (SO). The implantation window can also be assessed by monitoring of a natural cycle (NC). The objectives of this open randomized study is to compare the number of visits (ultrasound and blood tests) induced by the SO or NC as well as the women quality of life in both groups.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dr Massin Nathalie

Criteria

Inclusion Criteria:

• Affiliation to the general social security regime and benefiting from 100% infertility;

• Regular Cycles 26 to 35 days;

• Support in IVF or ICSI ;

• Existence of at least 2 frozen embryos to J2 or J3;

• Treated for their first or second cycle of TEC.

Exclusion Criteria:

• Donor sperm;

• Irregular cycles and / or polycystic ovary syndrome;

• Embryos frozen at J1 or J5 / J6 or double planned transfer or transfer of 3 embryos intended;

• Patients who have had more than 3 transfers or more than 6 embryos replaced without pregnancy or puncture rank> 3;

• uterine malformation existing;

• Presence of a hydrosalpinx.