Overview

Natural Killer(NK) Cell Therapy for Acute Myeloid Leukemia

Status:
Recruiting
Trial end date:
2025-10-21
Target enrollment:
Participant gender:
Summary
This is an open-label, Phase I study of QN-023a (allogeneic CAR-NK cells targeting CD33) in relapsed/refractory Acute Myeloid Leukemia (AML). The clinical study is to evaluate the safety, tolerability and preliminary efficacy of QN-023a in patients with relapsed/refractory AML,where a "3+3" enrollment schema will be utilized at dose escalation stage. Up to 18 patients will be enrolled.
Phase:
Phase 1
Details
Lead Sponsor:
Institute of Hematology & Blood Diseases Hospital
Collaborator:
Hangzhou Qihan Biotech Co.,Ltd.
Treatments:
Cyclophosphamide
Cytarabine
Fludarabine