Natural Supplements for Unipolar Depression

• Status: Completed
• Trial end date: 2008-09-17
• Target enrollment: 0
• Participant gender: All

Summary

This study is being conducted to determine the clinical response rate for the regimen of L-methionine, betaine and folate for unipolar depression.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cambridge Health Alliance
• Collaborator: National Alliance for Research on Schizophrenia and Depression
• Treatments: Betaine; Folic Acid; Vitamin B Complex

Criteria

Inclusion Criteria:

• DSM-IV diagnosis of a MDD or DDNOS; clinical indication for treatment of current depressive symptoms; HDS > 18; women of reproductive potential must use an acceptable method of birth control

Exclusion Criteria:

• Treatment with another psychotropic drug; history of mania or hypomania; history of bipolar illness in first-degree relatives; active homicidality; pregnant; trying to become pregnant, or nursing; unstable medical condition; current substance abuse in the past month; history of sulfa allergy