Overview

Natural Versus Artificial Cycle for Frozen-Thawed Embryo Transfer

Status:
Recruiting
Trial end date:
2023-06-01
Target enrollment:
0
Participant gender:
Female
Summary
This study evaluates clinical pregnancy rates, obstetrical outcome parameters, costs and patient preferences in natural cycle versus artificial cycle frozen embryo transfers (FET).
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Universitaire Ziekenhuizen Leuven
Collaborators:
GZA Ziekenhuizen Campus Sint-Augustinus
Imelda Hospital, Bonheiden
Jessa Hospital
Treatments:
Estradiol
Estradiol 17 beta-cypionate
Estradiol 3-benzoate
Polyestradiol phosphate
Progesterone
Criteria
Inclusion Criteria:

- Women undergoing FET after a first, second or third fresh IVF/ICSI cycle

- Single embryo transfer (SET) or Double embryo transfer (DET)

- Female age between 18-45 year

- Women having a natural ovulatory cycle (24-35 days)

- Normal uterine cavity (fundal indentation at the cavity <10mm)

- Written informed consent

Exclusion Criteria:

- Use of donor gametes

- BMI > or equal to 35 kg / m2

- Any contra-indication to estrogen or progesterone supplementation (e.g. history of
thrombosis, prior or current hormone-sensitive malignancy…)