Overview

Neadjuvant Multi-agent Chemotherapy or Letrozole Plus Ribociclib in Luminal B/HER2-negative Breast Cancer.

Status:
Completed
Trial end date:
2019-07-20
Target enrollment:
Participant gender:
Summary
CORALLEEN is a two-arm, randomized, multicentric study in postmenopausal women with primary HR+/HER2 negative Luminal B breast cancer that will explore if the combination of ribociclib with letrozole offers clinical benefit at least comparable to that of standard chemotherapy.
Phase:
Phase 2
Details
Lead Sponsor:
SOLTI Breast Cancer Research Group
Collaborator:
Novartis
Treatments:
Cyclophosphamide
Doxorubicin
Letrozole
Liposomal doxorubicin
Paclitaxel
Phenobarbital