Near Infrared Fluorescence Imaging With Indocyanine Green

• Status: Completed
• Trial end date: 2017-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This research study will evaluate how Near Infrared Fluorescence imaging (NIFI) with indocyanine green (ICG) contrast dye can assist in the identification and diagnosis of lung nodules during surgery. NIFI is an intraoperative imaging technology that utilizes a coupled camera/fluorophore (ICG) system to fluoresce tissues of interest. Intravenous ICG is a fluorophore with a long-standing high safety profile.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Pittsburgh

Criteria

Inclusion Criteria:

• Subjects must be willing to undergo surgical biopsy and/or resection of pulmonary nodule(s).

• Women and men at least 18 years of age

• Subjects must have a CT scan of the chest within 8 weeks of surgery

Exclusion Criteria:

• Previous thoracic surgery

• Inoperable tumor/nodule

• Unable to tolerate surgery

• History of allergies to iodides

• Breast feeding

• Pregnant