Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in the Emergency Department

• Status: Withdrawn
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective, randomized, controlled, double-blinded, clinical trial

Subject : 3mo ~ 24mo. aged infants with bronchiolitis

The effect of 3 % NaCl nebulizer or dexamethasone on admission rate of these infants in ED.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Epinephrine; Epinephryl borate; Racepinephrine

Criteria

Inclusion Criteria:

• 3mo ~ 24mo aged patients with bronchiolitis visit to emergency departments

• RDAI score 4-15

Exclusion Criteria:

• < 3mo, > 24mo

• infants who had received oral or inhaled corticosteroids during the preceding 2 weeks

• infants with a previous episode of wheezing or a diagnosis of asthma

• any chronic cardiopulmonary disease

• immunodeficiency

• infants needed intubation

• infants with a previous history of apnea or intubation

• infants with side effect of dexamethasone

• infants born at less than 37 weeks of gestation who had a corrected age of less than 6 weeks at presentation