Nebulized Hypertonic Saline Treatment in Hospitalized Children With Moderate to Severe Viral Bronchiolitis

• Status: Completed
• Trial end date: 2009-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is planned to investigate whether frequently inhaled hypertonic saline (HS) can relieve symptoms and signs faster than normal saline (NS) and shorten length of stay (LOS) significantly for moderately to severely ill infants with bronchiolitis without apparent adverse effects.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chongqing Medical University

Criteria

Inclusion Criteria:

• infants less than 24 months of age with first episode of wheezing.

Exclusion Criteria:

• age>24 months,

• previous episode of wheezing,

• chronic cardiac and pulmonary disease,

• immunodeficiency,

• accompanying respiratory failure,

• requiring mechanical ventilation,

• inhaling the nebulized 3% hypertonic saline solution 12 hours before treatment,

• premature infants born at less than 34 weeks gestation.