Overview Neo-adjuvant Chemo and Immunotherapy in the Pre-operAtive Treatment of Locally Advanced CholangIOcarciNoma Status: RECRUITING Trial end date: 2025-09-01 Target enrollment: Participant gender: Summary Neoadjuvant chemo- and immunotherapy ameliorate the recurrence rate of cholangiocarcinoma (CCA) at 12 months after surgery.Phase: PHASE2 Details Lead Sponsor: National Cancer Institute, NaplesTreatments: CisplatindurvalumabGemcitabine