Neo-adjuvant Therapy With Anastrozole Plus Pazopanib in Stage II and III ER+ Breast Cancer
Status:
Terminated
Trial end date:
2012-04-12
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well giving pazopanib hydrochloride and anastrozole before
surgery works in treating patients with stage II-III estrogen receptor-positive breast
cancer. Pazopanib hydrochloride and anastrozole may stop the growth of tumor cells by
blocking some of the enzymes needed for cell growth. Giving pazopanib hydrochloride and
anastrozole together before surgery may make the tumor smaller and reduce the amount of
normal cells that have to be removed