Neoadjuvant Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin Locally Advanced Rectal Cancer
Status:
Completed
Trial end date:
2019-03-01
Target enrollment:
Participant gender:
Summary
Phase II clinical trial, open-label, randomized, two arms, multicentre (possibly
multinational). Academic, investigator initiated.
To assess the activity of bevacizumab (AvastinTM) in combination with capecitabine (XelodaTM)
and radiation therapy with or without oxaliplatin (EloxatinTM) in the pre-operative treatment
of locally advanced rectal cancer, followed by TME (total mesorectal excision).