Neoadjuvant Chemoradiotherapy Followed By Surgery in Treating Patients With Limited-Stage Small Cell Lung Cancer
Status:
Completed
Trial end date:
2009-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy such as irinotecan and cisplatin use different ways to
stop tumor cells from dividing so they stop growing or die. Radiation therapy uses
high-energy x-rays to damage tumor cells. Irinotecan and cisplatin may also make the tumor
cells more sensitive to radiation therapy. Combining chemotherapy with radiation therapy
before surgery may shrink the tumor so that it can be removed during surgery.
PURPOSE: This phase I trial is studying the side effects of neoadjuvant radiation therapy
given together with irinotecan and cisplatin followed by surgery in treating patients with
limited-stage small cell lung cancer.