Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.
Status:
Recruiting
Trial end date:
2023-05-01
Target enrollment:
Participant gender:
Summary
Metformin is a widely used anti-diabetic drug. Several studies have pointed out a potentially
beneficial effect of metformin therapy in diabetic cancer patients. Several studies are
investigating the anti-tumor effect of metformin in early breast cancer. However, the
enhancing effect of metformin on anti-tumor immunity has only been demonstrated in animal
models. This study examines the immune effect of metformin in breast cancer patients treated
with preoperative chemotherapy.