Neoadjuvant Chemotherapy for Obstructive Colon cancER First Treated by cOlostomy
Status:
Not yet recruiting
Trial end date:
2031-01-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to determine whether chemotherapy prior to tumor removal
(neoadjuvant chemotherapy), in patients undergoing treatment for colon cancer in occlusion
(CCO), would improve the rate of patients able to benefit from "optimal" treatment, i.e.
complete treatment (including all neoadjuvant and adjuvant chemotherapy cures).
This new strategy, which would combine chemotherapy before surgery and possibly
post-operatively (depending on tumor analysis), could improve the prognosis of occluded colon
cancers by treating circulating micrometastases and/or inducing a reduction in tumor size,
thereby increasing the rate of complete resection.