Overview

Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ

Status:
Recruiting
Trial end date:
2028-08-01
Target enrollment:
Participant gender:
Summary
This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing neoadjuvant radiochemotherapy with FLOT versus FLOT chemotherapy alone für patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction (GEJ)
Phase:
Phase 3
Details
Lead Sponsor:
Universitätsmedizin Mannheim
Collaborators:
Deutsche Krebshilfe e.V., Bonn (Germany)
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Treatments:
Calcium
Docetaxel
Fluorouracil
Leucovorin
Levoleucovorin
Oxaliplatin