Neoadjuvant and Adjuvant Chemotherapy in High-risk Soft Tissue Sarcoma
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
Neo- and adjuvant chemotherapy is used in high-risk soft tissue sarcoma to improve systemic
control. Patients in this trial are treated with 4 cycles of chemotherapy (EIA, etoposide,
ifosfamide, adriamycin) preoperatively, followed by local surgery and radiotherapy. An
additional 4 cycles of adjuvant chemotherapy is administered. Treatment response is assessed
by MRI and CT scans and FDG-PET in a subgroup of patients.