Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function
Status:
Recruiting
Trial end date:
2026-07-01
Target enrollment:
Participant gender:
Summary
Current strategies for peripheral nerve repair are severely limited. Even with current
techniques, it can take months for regenerating axons to reach denervated target tissues when
injuries are proximally located. This inability to rapidly restore the loss of function after
axonal injury continues to produce poor clinical outcomes. The investigators propose testing
the efficacy and safety of a combination therapy: polyethylene glycol (PEG) assisted axonal
fusion technique to repair peripheral nerve injuries in humans.