Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety
Status:
Not yet recruiting
Trial end date:
2027-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this clinical trial is to answer the question: can the investigators predict
which adults with social anxiety disorder (SAD) will successfully respond to treatment? To
answer this question, the investigators plan to recruit 190 adult participants who experience
extreme forms of social anxiety to undergo brain imaging before and after 12 weeks of group
cognitive behavioral therapy (CBT). Adults in the SAD group who do not respond enough to
group CBT may be offered the opportunity to complete an additional 12 weeks of individual CBT
while receiving SSRI medication (sertraline, see below) for SAD.
Data collected from participants who experience anxiety will be compared to a group of 100
participants with little or no social anxiety, who will serve as a comparison group.
Phase:
N/A
Details
Lead Sponsor:
Boston University Charles River Campus
Collaborators:
Massachusetts Institute of Technology Mclean Hospital National Institute of Mental Health (NIMH)