Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers
Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
In imaging functional connectivity (FC) analyses of the resting brain, alterations of FC
during unconsciousness have been reported. These results are in accordance to recent
electroencephalographic studies observing impaired top-down processing during anesthesia. In
this study, simultaneous records of functional magnetic resonance imaging (fMRI) and
electroencephalogram (EEG) were performed to investigate the causality of neural mechanisms
during sevoflurane anesthesia by correlating FC in fMRI and directional connectivity (DC) in
electroencephalogram.