Neural and Behavioral Effects of Oxytocin in Autism Spectrum Disorders
Status:
Completed
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
The current trial aims to explore the neural and behavioral effects of oxytocin in autism
spectrum disorders (ASD). Oxytocin is a nonapeptide produced by the paraventricular and
supraoptic nuclei of the hypothalamus and is known to play a pivotal role in a variety of
complex social behaviors. Initial studies showed that intranasal administration of oxytocin
can have a positive effect on social functioning in ASD.
However, future studies are necessary to explore whether and how oxytocin effects neural
processes in the brain underlying these behavioral improvements. This trial will not only
measure behavioral enhancements, but will specifically focus on elucidating the associated
neurophysiological changes by guiding the administration of oxytocin with regular
neurophysiological assessments.
Phase:
Phase 4
Details
Lead Sponsor:
Katholieke Universiteit Leuven KU Leuven
Collaborators:
Branco Weiss Fellowship Research Foundation Flanders The Branco Weiss Fellowship