Neurobiological Bases of Placebo Response in Major Depressive Disorder
Status:
Terminated
Trial end date:
2016-08-01
Target enrollment:
Participant gender:
Summary
We are doing this research study to find out if people who get better while taking a specific
kind of antidepressant medication (a selective serotonin reuptake inhibitor, or SSRI) and
people who get better while taking placebo (an inactive substance) have similar chemicals in
their brains. Some participants may complete a procedure called Acute Tryptophan Depletion
(ATD), which is a way to study the role of serotonin in depression. Some participants may
also undergo a magnetic resonance-positron emission tomography (MR-PET) scan.