Neuromodulation and Language Acquisition (Project Stage Ia)

• Status: Terminated
• Trial end date: 2005-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether levodopa, pergolid, rivastigmine, or modafinil are effective in boosting semantic language acquisition in healthy subjects.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital Muenster
• Treatments: Levodopa; Modafinil; Rivastigmine

Criteria

Inclusion Criteria:

• Healthy subjects

• 20-35 years old

• Right handedness

• Left language dominance (as assessed by functional transcranial Doppler ultrasonography [fTCD])

Exclusion Criteria:

• Neurological/psychiatric/metabolic/cardiac disorders

• Asthma

• Known allergic reactions to one of the experimental drugs

• Other drugs affecting the central nervous system

• Leisure drug ingestion during the past 4 weeks (urine test)

• Smoking cessation during the past 2 weeks

• > 6 cups of coffee or energy drinks per day

• > 10 cigarettes per day

• > 50 grams of alcohol per day