Nicotinamide in the Treatment of Psoriasis

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine if combination of topical calcipotriol and nicotinamide is more effective than calcipotriol alone in treatment of psoriasis.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Isfahan University of Medical Sciences
• Treatments: Calcipotriene; Calcitriol; Niacin; Niacinamide; Nicotinic Acids

Criteria

Inclusion Criteria:

• Men and women of 18 to 65 years old,

• Mild to moderate psoriasis; patients must have had less than 15% of the involved body surface, symmetrical plaques (bilateral lesions) or two plaques at least 5 cm apart on the same side of the body with plaque size greater than 2 × 2 cm, but smaller than 15 × 15 cm.

• Willingness to participate

Exclusion Criteria:

• Those who used any medication or niacin and multi-vitamins two weeks, or anti-psoriatic systemic drugs or beta-blockers one month prior to the study,

• Pregnant women,

• Those with the history of renal, hematologic, liver and major psychiatric diseases,

• Those with only scalp, nail, flexural, palmoplantar, or pustular psoriasis.