Nifedipine Versus Magnesium Sulfate for Prevention of Preterm Labor in Symptomatic Placenta Previa

• Status: Completed
• Trial end date: 2021-04-30
• Target enrollment: 0
• Participant gender: Female

Summary

Antepartum hemorrhage is defined as bleeding from or within the female genital tract, occurring from 28+0 weeks of pregnancy and till delivery of the fetus. it occurs in 3-5% of pregnancies and is an important cause of perinatal and maternal morbidity and mortality worldwide

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Magnesium Sulfate; Nifedipine

Criteria

Inclusion Criteria:

• Estimated gestational age : between 28 weeks and 37 week's gestation

• Confirmed Placenta previa; either major or minor degrees.

• Placenta previa with preterm uterine contractions

Exclusion Criteria:

• Severe attack of bleeding requiring an immediate intervention.

• Fetal heart rates instability or non-reassuring tracing

• Intrauterine fetal death or major fetal anomalies.

• If associated with abruptio placentae

• Patients with known bleeding disorders or on anticoagulant therapy

• Patients with severe medical disorders as myasthenia gravis documented magnesium toxicity.